If the highest things are unknowable then the highest capacity or virtue of man cannot be theoretical wisdom.
Music can name the unnameable and communicate the unknowable.
Religion. A daughter of Hope and Fear explaining to Ignorance the nature of the Unknowable.
'Hamlet' is one of the most dangerous things ever set down on paper. All the big unknowable questions like what it is to be a human being the difference between sanity and insanity the meaning of life and death what's real and not real. All these subjects can literally drive you mad.
I have a great advantage over many of my colleagues inasmuch as my students bring with them to class their own personal knowledge of national regional religious ethnic occupational and family folklore traditions.