Learn to enjoy every minute of your life. Be happy now. Don't wait for something outside of yourself to make you happy in the future. Think how really precious is the time you have to spend whether it's at work or with your family. Every minute should be enjoyed and savored.
There's been a lot of really cool stuff that's happened to me throughout my career and I remember everything but I don't think I savored every moment of it like I should have or like I do now.
Most of the things we decide are not what we know to be the best. We say yes merely because we are driven into a corner and must say something.