I sort of try to write everything for me. I'm a huge sports fan but have no interest in minutiae. I don't remember who won Super Bowls five years ago or listen to sports talk radio. I'm trying to make sure the jokes are self-contained so they're accessible to everyone.
If you start using a medication in a person with autism you should see an obvious improvement in behavior in a short period of time. If you do not see an obvious improvement they probably should not be taking the stuff. It is that simple.