With acknowledgement of residues we can be more easily prepared to grant the unit of science the overlapping of disciplines and the total coherence of all facts.

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Well yeah. At a certain point you've got to be really honest with yourself. Like 'Why am I doing this? What are my motivations?' Like if you get into it because you want to be famous? Then you've got a long row to hoe. But if you really feel like it's a labour of love and it's something you're actually legitimately good at then it's not that hard to keep plugging away.