Our solution on 'The Simpsons' is to do jokes that people who have an education or some frame of reference can get. And for the ones who don't it doesn't matter because we have Homer banging his head and saying 'D'oh!'
A lot of what I've been learning in the last two years is due to therapy - about my sexuality why things go wrong why relationships haven't worked. It isn't anything to do with anybody else it's to do with me.